Brooke Pancake is a married woman and lives happily with her spouse. Derek Rende, who is also a golfer, is her husband. They do not have any children yet. She began her career as a member of the Crimson Tide. She won Southeastern Conference (SEC) championship in women's golf. She also led her Crimson Tide to National Championship in 2012. She was second individually with a 72-hole score of 2-under-par at 286. For her achievements in short period, she was honored with Honda Sports Award as the top collegiate golfer for the 2011–12 academic years and named as an All American for her play.
Just after completing senior session in Alabama, she became pro in June 2012. She than began to take part in various LPGA Tour.