In the early 1970s, Brian was seen with Margot Kidder having romantic love affairs with each other as a boyfriend and girlfriend. Margot Kidder is also an actress and an activist. She is popular for starring the role of Lois Lane in Superman.
After Brian called off his love life with Margot Kidder, he was seen with an American actress Nancy Allen. Nancy Allen is also an activist. They got married on 12th of January 1979. This married life lasted for about four years as they got divorced in 1983.
On 20th of July 1991, Brian got married for the second time in her life. Gale Anne Hurd is a renowned film producer from United States and the recipient of a star on the Hollywood Walk of Fame. They also welcomed a child from this married life named Lolita de Palma. They got divorced in 1993.
On 11th of October 1995, Brian tied his marriage knot with Darnell Gregorio-De Palma. Darnell Gregorio-De Palma is an actress popular for her work in Tarzan in Manhattan, Bad Dreams and so on. This married life also lasted for about one and half year. Brian has one brother named Bart DePalma, he doesn't have any sisters. His nationality is American.
Brian grew up in Philadelphia, Pennsylvania and New Hampshire. He received his formal education from Protestant and Quaker schools and finally earned his high school graduation from Friends' Central School. He is also the winner of a regional science-fair prize for building a computer. Initially he dreamed to be a physics student but later after watching Citizen Kane and Vertigo, he became interested in film making. He joined the theater department at the Sarah Lawrence College. In the early 1960s, he worked in the short movies like Icarus, 660124: The Story of an IBM Card, Woton's Wake and so on. In 1968, he worked in the movie Murder a la Mod as its director, writer and editor. He also directed and produced the movie Greetings in 1968 and for this work he earned his first nomination in Silver Berlin Bear. He is critically acclaimed for being the director of the movies like Dressed to Kill, Blow Out, The Untouchables and so on. He is now aged 75 years old and his net worth is $40 million.